Using α radiation to boost cancer immunity?

نویسندگان

  • Jean-Baptiste Gorin
  • Yannick Guilloux
  • Alfred Morgenstern
  • Michel Chérel
  • François Davodeau
  • Joëlle Gaschet
چکیده

Radioimmunotherapy aims to deliver radiation directly to cancer cells by means of a tumor specific vector coupled to a radionuclide. Alpha radionuclides are very potent agents to treat disseminated cancer and metastasis. We have demonstrated that α radiation can also induce immunogenic cell death, reinforcing interest in their clinical development.

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عنوان ژورنال:

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2014